Tespo Blog

What is methylfolate, and what are the benefits?

Posted by Tespo on Feb 7, 2018 7:01:00 AM

Folic acid, folate, methylfolate—it’s all the same right? Think again. Your body needs methylfolate: the purest form of Vitamin B9. Here's why.

Supplements come in all forms

Supplements include many ingredients, and while we talk a lot about “quality” what some people don’t realize is that ingredients can come in different forms. Because of this, our bodies can even react very differently to those different forms.

What is folate?

Folate, also known as Vitamin B9, comes in many variations. The body cannot produce folate, which requires us to get it from our food. Vegetables like spinach, broccoli and kale are rich in folate. But if we aren't getting it from our diet then we can take dietary supplements. Yet, the ingredient folic acid is actually the synthetic version of folate.

What is Methylfolate?

Methylfolate, which you can also take through supplementation, is the more active and natural form of folate. When we take folic acid, we rely on Methylenetetrahydrofolate reductase (MTHFR), which is both a gene and an enzyme found throughout our body to convert folic acid to its active form, L-methylfolate. This process is critical to the body having enough folate.

What are the benefits of Methylfolate?

Our body counts on methylfolate to produce red blood cells. A deficiency in folate can lead to anemia or a low red blood cell count. A deficiency during pregnancy can lead to birth defects. L-Methylfolate is also the only form of folate that can cross the blood-brain barrier to help facilitate the synthesis of the neurotransmitters associated with mood regulation—serotonin, dopamine and norepinephrine. A deficiency in L-Methylfolate has also been linked to depression, and therefore, taking a supplement containing Methylfolate can help fight against depression.

And it doesn’t stop there. The MTHFR gene and L-methylfolate also play many other roles in our body including repairing DNA, aiding the methylation cycle and in doing so supporting immune function, the body’s detoxification system, energy production and more. A failing methylation cycle has been associated with various autoimmune diseases, including autism. And if that’s not enough, MTHFR helps to control homocysteine, which is an amino acid that when not regulated or found in the body in high concentrations has been linked to heart attacks and stroke. Basically, a malfunctioning MTHFR gene can lead to a host of health problems very quickly.

So, why not just take folate?

There's nothing wrong with folate by itself, but here's the catch — because folate is a B vitamin, it is water-soluble. Some people have a gene mutation affecting the MTHFR enzyme. For these people, their bodies are unable to convert folic acid to Methylfolate. Therefore, it’s critical that they not take folic acid, but Methylfolate instead, to bypass the need to convert the folate.

If you have the gene mutation, or a digestive condition, and you are taking folic acid, you could end up with unmetabolized folic acid and Methylfolate competing for attention in your body which have been linked to poor immune function and a host of other health conditions.

Why Methylfolate is better than folate

At Tespo, we think there are just too many variables that can work against you when taking folic acid. Since the purpose of taking folic acid is for your body to ultimately convert it to Methylfolate, we say, ‘why not just use Methylfolate in the first place?’ Afterall, Methylfolate is the most effective form of folate to take. And if it’s that obvious, why don’t all dietary supplement companies use Methylfolate? Yes, you guessed it—Methylfolate is a more expensive, high-end ingredient. So be it. As part of our commitment to quality ingredients and quality products, we include Methylfolate in our Tespo-complete formulas at no extra cost to you. Why? Because at Tespo, your health is worth it to us.

Methylfolate is used in all of the Tespo complete formulas. The Tespo complete formulas are also enhanced with CoQ10, Lutein, and Zeaxanthin.

Tespo vitamins containing Methylfolate

Check out  all of the Tespo vitamins that contain Methylfolate. Can you tell that we like it? 😊

Tespo Women's Complete Multivitamin | $30/month
Tespo Men's Complete Multivitamin | $30/month
Tespo Women's Bariatric Complete Multivitamin | $48/month
Tespo Men's Bariatric Complete Multivitamin | $48/month
Tespo Hair, Skin & Nails | $25/month

Topics: Men's Health, Supplements, Tespo, Women's Health